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KHiMii reactor
KHiMii reactor

Flow chemistry

Most of the chemicals made for the fine or specialty chemical industry are made in batch.

Flow chemistry or continuous manufacturing can be the solution to some specific issues.

Questions Match with Flow chemistry if YES
Is the chemical reaction very exothermic or endothermic with a risk on safety or product quality? Flow chemistry is for you
Do you face an issue with yield, selectivity or purification in batch process? Flow chemistry can be a solution
Will the chemical reaction generate precipitates? Challenging but KHiMii can be the solution
Do you need to use some gas such as H2, O2, NH3, HF, Phosgene or Phosphine? Flow chemistry is for you
Does your reaction involve hazardous intermediates? Flow chemistry is for you
Is the reaction too slow and speed can be boosted at higher temperature or pressure? Flow chemistry is for you
Is the reaction very slow, even at high temperature or pressure? Flow chemistry is not an option


KHiMii flow reactors deliver 5 key benefits


  • Shorter time-to-market enabled by a seamless process scale-up
  • Ability to generate samples representative of the full-scale production


  • Precise control of the temperature even for extreme exothermic or endothermic reactions
  • Ability to safely handle liquids or gas even at very high pressure or temperature
  • Much smaller reaction volume than in batch process


  • Opportunity to dramatically reduce the use of solvents


  • Precise control of the mixing & temperature, delivering higher yield and selectivity
  • Option to use fixed bed catalysts

More cost effective

  • Lower CAPEX than in batch process due to smaller reactors, utilities and safety systems
  • Cost advantage even higher when high corrosion resistant metals are required
  • OPEX reduction with a faster reaction by working safely at high pressure or temperature
  • Ability to adjust the production CAPEX gradually, in line with the demand